Integrity™ PadMixer™
The Integrity™ PadMixer™ single-use mixing system is the most diverse system of its kind available today. The PadMixer system is designed for use in a manufacturing setting and performs equally well in product development. This single-use mixing system is efficient for all application types and offers high-end controls and abilities geared to satisfy cGMP requirements.
The PadMixer system uses an innovative bag design, allowing a non-invasive connection between the disposable mixing bag and the hardware. Mixing is initiated when the integrated paddle inside the bag rotates within. Speed, direction and frequency of rotational change can all be controlled by the operator and/or programmable recipe. The PadMixer system performs well for challenging mixing activities and is optimal for use in a broad range of bio- process applications, from buffer preparation to final formulation.
As with all ATMI LifeSciences' single-use mixing systems, the PadMixer system uses disposable mixing bags made for one-time use from ATMI Integrity TK8 bioprocess film. The product-contacting layer of Integrity TK8 film is blow-extruded in-house by ATMI under cleanroom conditions, using medical-grade ultra low-density polyethylene resin. It is then laminated to create a gas barrier film of exceptional cleanliness, strength and clarity that is animal derived component free (ADCF) and complies fully with USP Class VI requirements.
- Quicker time to market
- Rapid process changeover
- Faster development and production cycles
- cGMP focused with integrated, high-end controls and abilities
- Accommodates scaling from 5L to 1,000L (based on min. mix volume)
- Adjustable mixing paddle angle
- Easy-to-use touchscreen panel
- Reduced capital investment, higher ROI
- Increased throughput & improved facility utilization
- Ultra-clean; one contact material,
- Ensures materials integrity across mulit-product facilities
- Alternates mixing direction to increase mixing efficiency
- Program up to 100 different recipes
- Purification
- Suspension / re-suspension
- Harvesting
- Final formulation, fill
- Media, buffer preparation
Downloads
- Pad Mixer Brochure
- Pad-Drive Data sheet
- Film TK8
- Alhydrogel Mixing
- Cooling in a 200L Q-Mix Bag
- Demonstrating Scalability from 25L to 1000L
- Demonstrating Temperature Uniformity in Cubical Mix Bags
- Heating in a 25L Cubical Mixing Bag
- Heating in a 200L Cubical Mixing Bag
- Heating in a Part-Filled Cubical Mixing Bag
- High Viscosity Mixing
- Mixing a Diatomaceous Earth Slurry
- Mixing High Solid Load
- Mixing in Partially Filled Bag
- Mixing Uniformity
- Packing a Chromatography Column
- Strategies for Managing Exothermic Reactions